![]() Use of a Pipelle suction curette (flexible plastic curette used for minimally invasive tissue collection) has emerged as the most common method for endometrial tissue sampling, often indicated for evaluation of abnormal uterine bleeding, which is responsible for ~ 70% of all peri- and post-menopausal gynecological visits. ![]() Office vacuum aspiration (Pipelle) for endometrial biopsy (EMB) sampling plays an important role in early cancer diagnosis, preoperative assessment, and treatment planning for endometrial pathologies. Due to increasing obesity rates and little access to preventive services, EC mortality in Kazakhstan is higher than in comparison to the US and other developed countries. ConclusionĪnxiety during procedure performance was significantly associated with severe pain during the procedure but did not represent a key element for the success of Pipelle biopsy.Įndometrial cancer (EC) is the most common gynecologic malignancy in the developed world. We found no differences in Pipelle biopsy success rates in relationship to baseline, during and postprocedural pain and anxiety scores. Pain level was higher among patients sampled by the junior OB/GYN specialist ( p < 0.0001). Women who experienced severe pain during procedure tend to be more anxious during procedure ( p = 0.0001) and have higher number of sampling attempts ( p = 0.0040). ![]() Resultsģ.8%, 15.19% and 4.43% of women reported severe pain and 39.24%, 34.18% and 14.56% of women reported severe anxiety prior, during and after procedure, respectively. Women were asked to fill survey on pain, anxiety before, during and after the procedure. Study included 158 women with median age of 42 who underwent Pipelle endometrial biopsy at Clinical Academic Department of Women’s Health of the University Medical Center (UMC), Nur-Sultan City, Kazakhstan with an abnormal uterine bleeding from June 2019 to April 2021. The study's objective was to explore whether there is relationship between severe pain, anxiety, and the rate of Pipelle failure. The role of psychological factors such as anxiety and pain sensitivity in obtaining adequate samples is not well known. One of the reported disadvantages of sampling with Pipelle curette is failure to collect enough tissue for histological analysis. Pipelle endometrial biopsy is vital for the early diagnostics of endometrial pathology and is performed in outpatient setting in minimally invasive manner.
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